| Spanish slave traders of the early 16th Century | | | | young men returned to their respective groups to |
| were probably the first Europeans to interact with | | | | report their experiences. |
| the native population of Florida.[4] The first | | | | In 1620, a group of English settlers, including the |
| documented encounter of Europeans with Native | | | | Pilgrims, who were heading for the Hudson River, |
| Americans of the United States came with the | | | | got blown off-course and anchored in |
| first expedition of Juan Ponce de León to | | | | Provincetown Harbor before they settled at |
| Florida in 1513, although he encounted at least one | | | | present-day Plymouth, Massachusetts, instead, |
| native that spoke Spanish. In 1521, he | | | | during a harsh winter. In the autumn of 1621, they |
| encountered the Calusa people during a failed | | | | celebrated a three-day thanksgiving feast with |
| colonization attempt in which they drove off the | | | | the native Wampanoag people, without whom |
| Europeans. | | | | they would not have survived the winter of 1620. |
| In 1526, Lucas Vásquez de Ayllón tried | | | | The Great Migration continued into the 1630s and |
| to found a colony in what is now South Carolina, | | | | 40s, creating many settlements in New England |
| but for multiple reasons it failed after only a year. | | | | and the Virginia colony. Dutch colonization activities |
| The remaining slaves of the colony revolted and | | | | proceeded in an overlapping terr Pequot War |
| fled into the wilderness to live among the | | | | Meanwhile, Spanish and French colonization were |
| Cofitachiqui people. | | | | also proceeding on other areas of the continent. |
| The next encounter came with the members of | | | | Some European settlers used Native American |
| the Narváez expedition from | | | | contacts to further their activities in the fur trade; |
| 1528–1536. Ãlvar Núnez | | | | others sold European technology to the natives, |
| Cabeza de Vaca wrote a detailed account of the | | | | including firearms which fueled tribal wars. Peaceful |
| failed expedition which includes descriptions of | | | | coexistence was established in some times and |
| several Native American cultures he encountered | | | | places. For example, the careful diplomacy of |
| from Florida, the northern Gulf Coast, Texas, | | | | William Pynchon facilitated the founding of what |
| possibly New Mexico and Arizona, and northern | | | | would become Springfield, Massachusetts in a |
| Mexico. He described the behavior, living situation, | | | | desirable farming location close to the native |
| dress, and food of the people he encountered as | | | | Agawam settlement. |
| he wandered from village to village. | | | | Struggles for economic and territorial dominance |
| An expedition in 1539 headed by Fray Marcos de | | | | also continued to result in armed conflict. In some |
| Niza went in search of The Seven Cities of Gold. | | | | cases these latent conflicts resulted in escalating |
| They were guided by another survivor of the | | | | tensions, gradually followed by escalating |
| Narváez expedition, Estevanico, who | | | | multi-party violence. In other cases sudden, |
| encountered the Zuni people in his wanderings. | | | | relatively unprovoked raids were conducted on |
| Following de Niza in search of the fabled cities was | | | | native and colonial settlements, which might |
| Francisco Vásquez de Coronado from | | | | involve arson, massacre, or kidnapping for slavery. |
| 140–1542. He had encounters with the | | | | Pre-existing rivalries among both the Native |
| Hopi and Zuni as well as several other native | | | | American tribes and confederacies and the |
| groups in Arizona, New Mexico, Texas, Kansas, | | | | European nations led groups from both continents |
| and Oklahoma. | | | | to find war allies among the others against their |
| Also in 1539, the Hernando De Soto expedition | | | | traditional enemies. When transatlantic civilizations |
| traveled through the Southern United States from | | | | clashed, better technology (including firearms) and |
| 1539–1542. This expedition was | | | | the epidemics decimating native populations gave |
| responsible for introducing diseases into that | | | | Europeans a substantial military advantage. |
| region, and also resulted in several battles with | | | | In 1637, the Pequot War erupted in the |
| various tribes. The expedition included a member | | | | Massachusetts and Plymouth colonies. Indian Wars |
| of the failed Narváez expedition of 1528 | | | | in the English colonies would continue on and off |
| named Juan Ortiz who lived among the Tocobaga | | | | into the American Revolution. |
| people for twelve years before being rescued by | | | | In the early 1680s, Philadelphia was established by |
| de Soto. | | | | William Penn in the Delaware Valley, which was |
| Another encounter was the failed Roanoke | | | | home to the Lenni-Lenape nation. Chief Tamanend |
| Colony led by Sir Walter Raleigh of England in | | | | reputably took part in a peace treaty between |
| 1584. At first, the local tribes bartered with the | | | | the leaders of the Lenni-Lenape nation and the |
| colonists, but this was during a time of a severe | | | | leaders of the Pennsylvania colony held under a |
| drought, and when the local tribes grew more | | | | large elm tree at Shakamaxon. |
| reluctant to trade, relations deteriorated. The fate | | | | In the Spanish sphere, many of the Pueblo people |
| of the colonists is still a controversy. | | | | harbored hostility toward the Spanish, primarily |
| By 1578 there were about 350 European fishing | | | | due to their denigration and prohibition of the |
| vessels at Newfoundland and sailors began to | | | | traditional religion (the Spanish at the time being |
| trade metal implements (particularly knives) for | | | | staunchly and aggressively Catholic). The traditional |
| the natives' well worn pelts. The French fur trade | | | | economies of the pueblos were likewise disrupted |
| was undertaken by Francis Grave (a merchant) | | | | when they were forced to labor on the |
| and Chauvin (a captain) in 1599 when they | | | | encomiendas of the colonists. However, the |
| acquired a monopoly from Henry IV and their | | | | Spanish had introduced new farming implements |
| attempt to establish a colony at the mouth of the | | | | and provided some measure of security against |
| Saguenay River was a direct result of their desire | | | | Navajo and Apache raiding parties. As a result, |
| to profit from trading native fur pelts for | | | | they lived in relative peace with the Spanish |
| European goods. | | | | following the founding of the Northern New |
| England attempted again to colonize, first in 1606 | | | | Mexican colony in 1598. In the 1670s, however, |
| with the Popham Colony in present-day Maine, and | | | | drought swept the region, which not only caused |
| again in 1607 in Jamestown, Virginia. The latter | | | | famine among the Pueblo, but also provoked |
| became the first permanent English settlement in | | | | increased attacks from neighboring |
| the United States. The Popham Colony interacted | | | | hunter-gatherer tribes — attacks |
| with the Abeneki tribe, but failed to establish | | | | against which Spanish soldiers were unable to |
| cooperation. Jamestown's breakdown in relations | | | | defend. At the same time, European-introduced |
| with the Paspahegh and Powhatan tribes resulted | | | | diseases were ravaging the natives, greatly |
| in the First Anglo–Powhatan War, which | | | | decreasing their numbers. It has also been alleged |
| ended with the marriage of John Rolfe and | | | | that the introduction of these diseases was often |
| Pocahontas. | | | | exacerbated when soldiers handed out blankets |
| In 1610 a teenage Étienne Brulé was | | | | and other humanitarian supplies carrying European |
| sent by Samuel de Champlain to live with the | | | | microorganisms.[citation needed] Unsatisfied with |
| Hurons for a year as a sort of 'exchange student'. | | | | the protective powers of the Spanish crown, the |
| Champlian, in turn, accepted the company of a | | | | Pueblo revolted in 1680. In 1692, Spanish control |
| Huron youth named Savignon who accompanied | | | | was reasserted, but under much more lenient |
| him back to France. The two cultures made a | | | | terms. |
| successful rendezvous the next year and the | | | | |